Are “Juice Detoxes” Healthy?

Juice fasts, also known as ‘juice cleanses’ or j’uice detoxes’, involve consuming only fruit and vegetable juices for a certain period, while abstaining from solid foods. These diets are promoted as a way to ‘detoxify’ the body, lose weight, and ‘improve overall health’. However, the effectiveness of juice fasts is dubious at best, so it’s important to review the logic behind them.

What juice fasts claim to do:

  1. Detoxification: Advocates of juice fasts claim that they help the body ‘detoxify’ by eliminating toxins and waste products. They argue that the concentrated nutrients in the juices can support the body’s natural ‘detoxification’ processes.
  2. Weight Loss: Juice fasts can lead to a rapid reduction in calorie intake, which can result in short-term weight loss. Proponents argue that this can jumpstart a ‘healthier eating pattern’.
  3. Improved Health: Some proponents suggest that juice fasts can lead to improved digestion, increased energy, clearer skin, and other health benefits.

The reality today:

  1. Lack of Scientific Evidence: There is limited scientific evidence to support the claims made by juice fast proponents. ‘Detox’ diets, in general, lack rigorous scientific backing, and the body has its natural detoxification mechanisms such as the liver and the kidneys. Many juice detox supporters also do not specify what ‘toxins’ they are actually trying to eliminate. In fact, it has long been regarded that the best way to let the body reach a natural state of healing and repair is fasting from food althogether (refer to prior blog). If we look to nature, many animals who take ill refrain from eating for a period of time.
  2. Nutritional Deficiencies: Juice fasts can lead to nutrient deficiencies, particularly in protein, fiber, and essential vitamins and minerals. Prolonged juice fasting can thus have negative health consequences.
  3. Short-Term Weight Loss, Long-Term Gain: While juice fasts can lead to short-term weight loss, this weight may be regained once solid foods are reintroduced. This is because juice diets are hard to sustain and often too low in calories.
  4. Hunger and Fatigue: Many people find juice fasts difficult to stick to due to hunger and fatigue, due to the low calories, fat and protein, and this can result in low energy levels, metabolism and irritability.
  5. Potential Health Risks: Juice fasts may not be safe for everyone, particularly those with underlying health conditions, and can potentially lead to electrolyte / salt imbalances, dizziness, and other adverse effects.

Fructose is a natural sugar found in many fruits, vegetables, and honey. It is a simple sugar, or monosaccharide, and plays a role in various physiological processes within the body. The digestion of fructose primarily occurs in the liver, and here’s how it is processed:

  1. Absorption in the Small Intestine: When you consume foods or beverages containing fructose, it travels to your small intestine, where digestion begins. Fructose is primarily absorbed in the small intestine, but it requires a specific transport protein called GLUT5 (Glucose Transporter 5) to facilitate its absorption.
  2. Transport to the Liver: After absorption, fructose is transported to the liver via the bloodstream. Unlike glucose, which can be used by various cells throughout the body, fructose is almost exclusively metabolised in the liver.
  3. Metabolism in the Liver: In the liver, fructose is processed through a series of enzymatic reactions. One of the key enzymes involved in fructose metabolism is fructokinase, which converts fructose to fructose-1-phosphate. Another enzyme, aldolase B, cleaves fructose-1-phosphate into dihydroxyacetone phosphate and glyceraldehyde.
  4. Conversion to Glucose or Fat: The products of fructose metabolism in the liver can be used for different purposes. Some of the glyceraldehyde can be converted to glucose, while dihydroxyacetone phosphate can be used for glycerol synthesis, which is a component of triglycerides (fat molecules). This means that fructose can contribute to both glucose production and fat storage in the liver.
  5. Energy Production: The energy stored in fructose can be used by the liver for various metabolic processes or stored for future energy needs.
  6. Excretion: Any excess fructose that is not immediately metabolised or used for energy can be converted into glucose or stored as fat. This can lead to various metabolic consequences, especially if fructose intake is excessive over an extended period.
While juice may be rich in vitamins, it can spike blood sugar very quicky, causing any excess blood sugar or fructose to be converted to fat by the liver. As such, it is often recommended that carbohydrates be consumed with ample fibre, protein and fat as part of a balanced meal.

It’s important to note that excessive consumption of fructose, particularly in the form of high-fructose corn syrup found in many processed foods and sugary beverages, has been associated with negative health effects.

Excessive fructose intake can contribute to fatty liver disease, insulin resistance, and other metabolic issues. Therefore, it’s recommended to consume fructose in moderation as part of a balanced diet and to focus on whole foods rather than processed sources of fructose. ‘Off the shelf’ fruit juices are often laden with hidden additives and sugar in order to preserve their shelf life. This can spike blood sugar levels very quicky.

Additionally, individuals with hereditary fructose intolerance, a rare genetic disorder, lack the enzyme aldolase B and are unable to metabolize fructose properly. In such cases, fructose consumption can lead to severe health problems, and individuals with this condition must avoid fructose-containing foods entirely.

In general, juice fasts are not a long-term solution for weight loss or improved health. Although as with any dietary change, it’s important to consider the big picture; how long is the fast? What are the specific goals? How many calories are being consumed? It’s also important to consider working with a healthcare professional such as a dietician before embarking on any extreme dietary changes, most especially if you have underlying health issues.

It’s important to be critical of the sources of information about juice fasts and consider the lack of substantial scientific evidence supporting many of the ‘detox’ claims. A balanced and sustainable approach to nutrition and weight management, based on whole foods, is often a more advisable and healthier option.

If you or a friend needs support with your health and fitness goals, why not speak to one of our registered health professionals at Destiny Health today? Simply book your Free Assessment (with no sales pressure) from our home page. Online or in-person options are available.

It’s Destiny Health, where ‘Goals Make Destiny.’


  1. Klein, A. V., & Kiat, H. (2015). Detox diets for toxin elimination and weight management: a critical review of the evidence. Journal of Human Nutrition and Dietetics, 28(6), 675-686.
  2. Gatenby, S. J., & Aaron, J. G. (2015). Eating for weight loss: the dietetics of detox. Journal of Human Nutrition and Dietetics, 28(2), 126-133.
  3. Institute of Medicine. (2005). Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. The National Academies Press.
  4. American Heart Association. (2015). Diet and lifestyle recommendations. Retrieved from